Publications | Biophotonic Imaging Laboratory

Books

1. Y. Chen, B. Katab, Eds., “Neurophotonics and Brain Mapping,” Taylor & Francis Books (in press).

Book Chapter

1. J.G. Fujimoto, A. Aguirre, Y. Chen, P. Herz, P. Hsiung, T. Ko, N. Nishizawa, F. Kaertner, “Ultrahigh Resolution Optical Coherence Tomography using Femtosecond Lasers,” in Ultrashort Laser Pulse in Biology and Medicine, M. Braun, P. Gilch, W. Zinth, Eds., Springer (2007).

2. J.G. Fujimoto, Y. Chen, A. Aguirre, “Biomedical Imaging using Optical Coherence Tomography, ” in Biomedical Optics Handbook, Oxford University Press (2008).

3. A. Unterhuber, B. Povazay, A. Aguirre, Y. Chen, F.X. Kartner, J.G. Fujimoto, W. Drexler, “Broad Bandwidth Laser and Nonlinear Optical Light Sources for OCT, ” in Optical Coherence Tomography: Technology and Applications, J.G. Fujimoto and W. Drexler, Eds., Springer (2008).

4. W. Drexler, Y. Chen, A. Aguirre, B. Povazay, A. Unterhuber, J.G. Fujimoto, “Ultrahigh Resolution Optical Coherence Tomography, ” in Optical Coherence Tomography: Technology and Applications, J.G. Fujimoto and W. Drexler, Eds., Springer (2008).

5. Y. Chen, A.D. Aguirre, D. Adler, H. Mashimo, J.G. Fujimoto, “Endoscopy, ” in Translational Multimodality Optical Imaging, X. Intes, F. Azar, Eds., Artech House (2008).

6. S. Yuan, Y. Chen, “Optical Coherence Tomography Based Multi-Modal Optical Imaging in Biomedical Applications, ” in Advances in Lasers and Electro Optics, V. Kordic, Ed., IN-TECH (2010).

7. Y. Chen, E. Bousie, C. Pitris, J.G. Fujimoto, “Optical Coherence Tomography: Introduction and Theory, ” in Handbook of Biomedical Optics, D.A. Boas, C. Pitris, N. Ramanujam, Eds., Taylor & Francis Books (2011).

8. Y. Chen, “Clinical Diffuse Optical Imaging: Techniques and Applications, ” in McGraw Hill Series in Biophotonics: In Vivo Clinical Imaging and Diagnosis, J. W. Tunnel, Ed., McGraw Hill (2011).

9. Y. Chen, U. Balis, L. Pantanowitz, “Advanced Imaging Techniques, ” in Pathology Informatics: Modern Practice & Theory for Clinical Laboratory Computing, L. Pantanowitz, Ed., American Society of Clinical Pathology Press (2012).

10. C.W. Chen, Y. Chen, “Multi-Modal Tomography Combining Optical Coherence Tomography (OCT) with Fluorescence Laminar Optical Tomography (FLOT), ” in Advanced Biophotonics: Slicing Tissue with Photons, V. Tuchin and R. Wang, Eds., Taylor & Francis Books (2012).

11. C.W. Chen, Y. Chen, “Multi-Modal Mesoscopic Tomography Combining Optical Coherence Tomography (OCT) with Fluorescence Laminar Optical Tomography (FLOT), ” in Optical Coherence Tomography: Technology and Applications (2nd Ed.), J.G. Fujimoto and W. Drexler, Eds., Springer (2015).

12. P.M. Andrews, J. Wierwille, Y. Chen, “Optical Coherence Tomography in Kidney Transplantation, ” in Optical Coherence Tomography: Technology and Applications (2nd Ed.), J.G. Fujimoto and W. Drexler, Eds., Springer (2015).

13. H. Guo, Y. Chen, “Advanced Imaging, ” in Digital Pathology, L. Pantanowitz and A. Parwani, Eds., American Society of Clinical Pathology Press (2016)

14. Z. Li, Q. Tang, B. Wang, Y. Chen, “Optical Coherence Tomography, ” in Encyclopedia of Medical Robotics, Vol. Image-guided Surgical Procedures and Interventions, J.P. Desai, Ed., World Scientific Publishing Company (in press).

15. B. Kateb, F. Boehm, V. Tsytsarev, Y. Chen, “History of Brain Mapping and Neurophotonics, ” in Neurophotonics and Brain Mapping, Chen and Kateb, Eds., Taylor & Francis Books (in press).

16. C.P. Liang, C.M. Tang, Y. Chen, “Intra-operative Optical Guidance for Neurosurgery, ” in Neurophotonics and Brain Mapping, Chen and Kateb, Eds., Taylor & Francis Books (in press).

Journal Paper

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1. Y. Chen, S. Zhou, C. Xie, S. Nioka, M. Papadopoulos, E. Anday, B. Chance, “Preliminary Evaluation of Dual Wavelength Phased Array Imaging on Neonatal Brain Function,” Journal of Biomedical Optics, 5, 194-200 (2000).

2. Y. Chen, C. Mu, X. Intes, B. Chance, “Signal-to-Noise Analysis for Detection Sensitivity of Small Absorbing Heterogeneity in Turbid Media with Single-source and Dual-Interfering-Source,” Optics Express, 9, 212-224 (2001).

3. X. Intes, Y. Chen, X. Li, B. Chance, “Detection Limit Enhancement of Florescent Heterogeneities in Turbid Media by Dual Interfering Excitation,” Applied Optics, 41, 3999

4. T. Tu, Y. Chen, J. Zhang, X. Intes, B. Chance, “Analysis of Performance and Optimization of Frequency-Domain Near-Infrared Instruments,” Journal of Biomedical Optics, 7, 643-649 (2002).

5. Y. Chen, C. Mu, X. Intes, B. Chance, “Adaptive Calibration for Object Localization in Turbid Media with Interfering Diffuse Photon Density Waves,” Applied Optics, 41, 7325-7333 (2002).

6. Y. Chen, X. Intes, D. Tailor, R. Regatte, H. Ma, V. Ntziachristos, J. Leigh, R. Reddy, B. Chance, “Probing Rat Brain Oxygenation with Near-Infrared (NIR) Spectroscopy and Magnetic Resonance Imaging (MRI),” Advances in Experimental Medicine and Biology, 510, 199-204 (2003).

7. Y. Chen, D. Tailor, X. Intes, B. Chance, “Correlation between Near-Infrared Spectroscopy and Magnetic Resonance Imaging of Rat Brain Oxygenation Modulation,” Physics in Medicine and Biology, 48, 417-427 (2003).

8. X. Intes, J. Ripoll, Y. Chen, S. Nioka, A.G. Yodh, B. Chance, “In Vivo Continuous Wave Optical Breast Imaging Enhanced by Indocyanine Green,” Medical Physics, 30, 1039-1047 (2003).

9. Y. Chen, C. Mu, X. Intes, D. Blessington, B. Chance, “Near-Infrared Phase Cancellation Instrument for Fast and Accurate Localization of Fluorescent Heterogeneity,” Review of Scientific Instruments, 74, 3466-3473 (2003).

10. Y. Chen, G. Zheng, Z. Zhang, D. Blessington, Q. Liu, X. Intes, L. Zhou, H. Li, M. Zhang, S. Achilefu, B. Chance, “Metabolism Enhanced Tumor Localization by Fluorescence Imaging: In Vivo Animal Studies,” Optics Letters, 28, 2070-2072 (2003).

11. G. Zheng, Y. Chen, X. Intes, B. Chance, J.D. Glickson, “Contrast-Enhanced Near-Infrared (NIR) Optical Imaging for Subsurface Cancer Detection,” Journal of Porphyrins and Phthalocyanines, 8, 1106-1117 (2004). Review Paper

12. P.R. Herz, Y. Chen, A. Aguirre, K. Schneider, P. Hsiung, K. Madden, J. Schmitt, J. Goodnow, C. Petersen, J.G. Fujimoto, “Micro-Motor Endoscope Catheter for In Vivo Ultrahigh Resolution Optical Coherence Tomography,” Optics Letters, 29, 2261-2263

13. N. Nishizawa, Y. Chen, P. Hsiung, E.P. Ippen, J.G. Fujimoto, “All-Fiber Real-Time High-Resolution Optical Coherence Tomography using High-Power Low Noise Super Continuum at 1.55 ïm,” Optics Letters, 29, 2846-2848 (2004).

14. P. Hsiung, Y. Chen, T.H. Ko, J.G. Fujimoto, C.J.S. de Matos, S.V. Popov, J.R. Taylor, V.P. Gapontsev, “Optical Coherence Tomography using a Continuous-Wave, High-Power, Raman Continuum Light Source,” Optics Express, 12, 5287-5295 (2004).

15. P.R. Herz, Y. Chen, A. Aguirre, J.G. Fujimoto, H. Mashimo, J. Schmitt, A. Koski, J. Goodnow, C. Petersen, “Ultrahigh Resolution Optical Biopsy with Endoscopic Optical Coherence Tomography,” Optics Express, 12, 3532-3542 (2004).

16. Y. Chen, X. Intes, B. Chance, “Development of High Sensitivity Near-Infrared (NIR) Fluorescence Imaging Device for Early Cancer Detection,” Biomedical Instrumentation and Technology, 39, 75-85 (2005). Outstanding Instrumentation Research Paper

17. P. Hsiung, L. Pantanowitz, A.D. Aguirre, Y. Chen, D. Phatak, J.L. Connolly, H. Mashimo, J.G. Fujimoto, “Ultrahigh Resolution and 3D Optical Coherence Tomography Ex Vivo Imaging of the Large and Small Intestine,” Gastrointestinal Endoscopy, 62, 561-574 (2005).

18. B. Chance, Z. Zhao, S. Wen, Y. Chen, “Simple AC Circuit for Breast Cancer Detection and Object Detection,” Review of Scientific Instruments, 77, 064301 (2006).

19. A.D. Aguirre, Y. Chen, L. Ruvinskaya, A. Devor, D.A. Boas, J.G. Fujimoto, “Cross-sectional Imaging of Functional Activation in the Rat Somatosensory Cortex with Optical Coherence Tomography,” Optics Letters, 31, 3459-3461 (2006).

20. A.D. Aguirre, P.R. Herz, Y. Chen, J.G. Fujimoto, W. Piyawattanametha, L. Fan, M.C. Wu, “Two-Axis MEMS Scanning Catheter for Ultrahigh Resolution Three-Dimensional and En Face Imaging,” Optics Express, 15, 2445-2453 (2007).

21. Y. Chen, P.M. Andrews, A.D. Aguirre, J.M. Schmitt, J.G. Fujimoto, “High-Resolution Three-Dimensional Optical Coherence Tomography Imaging of Kidney Microanatomy Ex Vivo,” Journal of Biomedical Optics, 12, 034008 (2007).

22. Y. Chen, A.D. Aguirre, P. Hsiung, S. Desai, P.R. Herz, M. Pedrosa, Q. Huang, M. Figueiredo, S. Huang, A. Koski, J.M. Schmitt, J.G. Fujimoto, H. Mashimo, “Ultrahigh Resolution Optical Coherence Tomography of Barrettâ€™s Esophagus â€“ Preliminary Descriptive Clinical Study Correlating Images with Histology,” Endoscopy, 39, 599-605 (2007). Featured on Journal Cover

23. Y. Chen, S. Huang, A.D. Aguirre, J.G. Fujimoto, “High-Resolution Line-Scanning Optical Coherence Microscopy,” Optics Letters, 32, 1971-1973 (2007).

24. P. Hsiung, D. Phatak, Y. Chen, A.D. Aguirre, L. Pantanowitz, J.G. Fujimoto, J.L. Connolly, “Ultrahigh Resolution and 3D Optical Coherence Tomography Ex Vivo Imaging of Malignant and Benign Lesions in Human Breast,” Radiology, 244, 865-874 (2007).

25. D. Adler, Y. Chen, R. Huber, J.M. Schmitt, J. Connolly, J.G. Fujimoto, “Three-Dimensional Endomicroscopy with Optical Coherence Tomography,” Nature Photonics, 1, 709-716 (2007).

26. Y. Chen, A.D. Aguirre, P. Hsiung, S. Huang, H. Mashimo, S. Desai, J. Schmitt, J.G. Fujimoto, “Effects of axial resolution improvement on optical coherence tomography (OCT) imaging of gastrointestinal tissues,” Optics Express, 16, 2469-2485 (2008).

27. P.M. Andrews, Y. Chen, S. Huang, D. Adler, R. Huber, J. Jiang, S. Barry, A. Cable, J.G. Fujimoto*, “High-Speed Three-Dimensional Optical Coherence Tomography Imaging of Kidney Ischemia In Vivo,” Laboratory Investigation, 88, 441-449 (2008).

28. Y. Chen, A.D. Aguirre, L. Ruvinskaya, A. Devor, D.A. Boas, J.G. Fujimoto, “Depth-Resolved Functional Imaging of Rat Somatosensory Cortex with Optical Coherence Tomography,” Journal of Neuroscience Methods, 178, 162-173(2009).

29. C. Zhou, D.C. Adler, L. Becker, Y. Chen, T.H. Tsai, M. Figueiredo, J.M. Schmitt, J.G. Fujimoto, H. Mashimo, “Effective treatment of chronic radiation proctitis using radiofrequency ablation,” Therapeutic Advances in Gastroenterology, 2, 149-156 (2009).

30. S. Yuan, Q. Li, J. Jiang, A. Cable, Y. Chen, “Three-Dimensional Co-Registered Optical Coherence Tomography and Line-Scanning Fluorescence Laminar Tomography,” Optics Letters, 34, 1615-1617 (2009).

31. Q. Li, M.L. Onozato, P.M. Andrews, C.W. Chen, A. Paek, R. Naphas, S. Yuan, J. Jiang, A. Cable, Y. Chen, “Automated Image Analysis of Three-Dimensional Microstructures of the Human Kidney using Optical Coherence Tomography (OCT),” Optics Express, 17, 16000-16016 (2009).

32. C.W. Chen, T. Blackwell, R. Naphas, P. Winnard, V. Raman, K. Glunde, Y. Chen, “Development of Needle-Based Microendoscopy for Fluorescence Molecular Imaging of Breast Tumor,” Journal of Innovation in Optical Health Sciences, 2, 343-352 (2009).

33. A.D. Aguirre, Y. Chen, B. Bryan, H. Mashimo, Q. Huang, J.L. Connolly, J.G. Fujimoto, “Cellular Resolution Ex Vivo Imaging of Gastrointestinal Tissues with Optical Coherence Microscopy,” Journal of Biomedical Optics, 15, 016025 (2010).

34. S. Yuan, C.A. Roney, J. Wierwille, C.W. Chen, B. Xu, G. Griffiths, J. Jiang, Q. Li, H. Ma, A. Cable, R.M. Summers, Y. Chen, “Co-registered Optical Coherence Tomography and Fluorescence Molecular Imaging for Simultaneous Morphological and Molecular Imaging,” Physics in Medicine and Biology, 55, 191-206 (2010).

35. M.L. Onozato, P.M. Andrews, Q. Li, J. Jiang, A. Cable, Y. Chen, “Optical Coherence Tomography Imaging of Intact Human Kidney Ex-Vivo,” Journal of Urology, 183, 2090-2094 (2010).

36. Y. Chen, S. Yuan, J. Wierwille, R. Naphas, Q. Li, T. Blackwell, P. Winnard, V. Raman, K. Glunde, “Integrated Optical Coherence Tomography (OCT) with Fluorescence Laminar Optical Tomography (FLOT),” IEEE Journal of Selected Topics in Quantum Electronics, 16, 755-766 (2010). Invited Paper

37. K.A. DiVito, V.A. Trabosh, Y.S. Chen, C. Albanese, Y. Chen, A. Mauviel, C.M. Simbulan-Rosenthal, D.S. Rosenthal, “Smad7 Suppresses N-cadherin Cleavage in Metastatic Melanoma Through Î²-catenin Stabilization and Restores Heterotypic Cell-Cell Interactions In Vivo,” Pigment Cell & Melanoma Research, 23, 795-808 (2010).

38. C.W. Chen, M.W. Betz, J.P. Fisher, A. Paek, Y. Chen, “Macroporous Hydrogel Scaffolds and Their Characterization By Optical Coherence Tomography,” Tissue Engineering â€“ Part C: Methods, 17, 101-112 (2011).

39. C.A. Roney, B. Xu, J. Xie, S. Yuan, J. Wierwille, C.W. Chen, Y. Chen, G.L. Griffiths, R.M. Summers, “Rh-I-UEA-1 Polymerized Liposomes Target and Image Adenomatous Polyps in the APCMin/+ Mouse using Optical Colonography,” Molecular Imaging, 10, 305-316 (2011). Featured on Journal Cover

40. C.W. Chen, Y. Chen, “Optimization of Design Parameters for Fluorescence Laminar Optical Tomography,” Journal of Innovation in Optical Health Sciences, 4, 309-323 (2011).

41. J. Wierwille, P.M. Andrews, M. Onozato, J. Jiang, A. Cable, Y. Chen, “In vivo, label-free, three-dimensional quantitative imaging of kidney microcirculation using Doppler optical coherence tomography (DOCT),” Laboratory Investigation, 91, 1596-1604 (2011).

42. C.P. Liang, J. Wierwille, T. Moreira, G. Schwartzbauer, M.S. Jafri, C.M. Tang, Y. Chen, “A Forward-Imaging Needle-Type OCT Probe for Image Guided Stereotactic Procedures,” Optics Express, 19, 26283-26294 (2011).

43. Y. Chen, S.W. Huang, C. Zhou, B. Potsaid, J.G. Fujimoto, “Improved Detection Sensitivity of Line-Scanning Optical Coherence Microscopy,” IEEE Journal of Selected Topics in Quantum Electronics, 18, 1094-1099 (2012). Invited Paper

44. C.P. Liang, C.W. Chen, J. Desai, R. Gullapalli, C.M. Tang, R. Mezrich, Y. Chen, “Endoscopic Microscopy Using Optical Coherence Tomography,” Current Medical Imaging Reviews, 8, 174-193 (2012). Review Paper

45. Y. Chen, C.P. Liang, Y. Liu, A.V. Parwani, A.H. Fischer, L. Pantanowitz, “Review of Advanced Imaging Techniques”, Journal of Pathology Informatics, 3, 22 (2012). Review Paper

46. E. Ayvali, C.P. Liang, M.Y. Ho, Y. Chen, J. Desai, “Towards a Discretely Actuated Steerable Cannula for Diagnostic and Therapeutic Procedures,” International Journal of Robotics Research, 31, 588-603 (2012).

47. A. Agrawal, M. Connors, A. Beylin, C.P. Liang, D. Barton, Y. Chen, R.A. Drezek, T.J. Pfefer, “Characterizing the Point Spread Function of Retinal OCT Systems with a Model Eye-Based Phantom,” Biomedical Optics Express, 3, 1116-1126 (2012).

48. R. M. Lovering, S.B. Shah, S.J.P. Pratt, W. Gong, Y. Chen, “Architecture of Healthy and Dystrophic Muscles Detected by Optical Coherence Tomography,” Muscle and Nerve, 47, 588-590 (2013).

49. Y. Chen, H. Guo, W. Gong, L. Qin, H. Aleyasin, R.R. Ratan, S. Cho, J. Chen, S. Xie, “Recent Advances in Two-Photon Imaging: Technology Developments and Biomedical Applications,” Chinese Optics Letters, 11, 011703 (2013). Review Paper

50. C.P. Liang, B. Yang, I.K. Kim, G. Makris, J.P. Desai, R.P. Gullapalli, Y. Chen, “Concurrent Multiscale Imaging with Magnetic Resonance Imaging and Optical Coherence Tomography,” Journal of Biomedical Optics, 18, 046015 (2013).

51. C.P. Liang, Y. Wu, J. Schmitt, P.E. Bigeleisen, J. Slavin, M.S. Jafri, C.M. Tang, Y. Chen, “Coherence-gated Doppler: a Fiber Sensor for Precise Localization of Blood Flow,” Biomedical Optics Express, 4, 760-771 (2013).

52. A. Agrawal, C.W. Chen, J. Baxi, Y. Chen, T. J. Pfefer, “Multilayer thin-film phantoms for axial contrast transfer function measurement in optical coherence tomography,” Biomedical Optics Express, 4, 1166-1175 (2013).

53. H. Guo, H. Aleyasin, S.S. Howard, B.C. Dickinson, V.S. Lin, R.E. Haskew-Layton, C. Xu, Y. Chen, R.R. Ratan, “Two-photon fluorescence imaging of intracellular hydrogen peroxide with chemoselective fluorescent probes,” Journal of Biomedical Optics, 18, 106002 (2013).

54. P.M. Andrews, H.W. Wang, J. Wierwille, W. Gong, J. Verbesey, M. Cooper, Y. Chen, “Optical Coherence Tomography of the Living Human Kidney,” Journal of Innovative Optical Health Sciences, 7, 1350064 (2014).

55. P.M. Andrews, Y. Chen, “Evaluating Donor Kidneys for Transplantation using Optical Coherence Tomography (OCT),” Journal of Nephrology and Therapeutics, 4, 1000151 (2014). Review Paper

56. H.W. Wang, Y. Chen, “Clinical Applications of Optical Coherence Tomography in Urology,” Intravital, 3, e28770 (2014). Review Paper

57. J. Wang, J. Coburn, C.P. Liang, N. Woolsey, J.C. Ramella- Roman, Y. Chen, T.J. Pfefer, “Three-Dimensional Printing of Tissue Phantoms for Biophotonic Imaging,” Optics Letters, 39, 3010-3013 (2014).

58. A. Fouad, J. Pfefer, C.W. Chen, W. Gong, A. Agrawal, P. Tomlins, P. Woolliams, R. Drezek, Y. Chen, “Variations in Optical Coherence Tomography Resolution and Uniformity: A Multi-System Performance Comparison.” Biomedical Optics Express, 5, 2066â€“2081 (2014).

59. P.M. Andrews, M. Cooper, J. Verbesey, S. Ghasemian, D. Rogalsky, P. Moody, A. Chen, P. Alexandrov, H.W. Wang, Y. Chen, “Mannitol Infusion within 15 min of Cross-Clamp Improves Living Donor Kidney Preservation,” Transplantation, 98, 893â€“897 (2014).

60. C.P. Liang, Y. Chen, T. Nakajima, R. Watanabe, K. Sato, P.L. Choyke, H. Kobayashi, “Real-time Monitoring of Photo-immunotherapy Using Optical Coherence Tomography,” Journal of Biomedical Optics, 19, 098004 (2014).

61. S.K. Han, C.W. Chen, J. Wierwille, Y. Chen, A.H. Hsieh, “Three Dimensional Mesoscale Analysis of Translamellar Cross-Bridge Morphologies in the Annulus Fibrosus using Optical Coherence Tomography,” Journal of Orthopaedic Research, 33, 304-311 (2015).

62. Z. Ding, C.P. Liang, Y. Chen, “Technology Developments and Biomedical Applications of Polarization-Sensitive Optical Coherence Tomography,” Frontiers of Optoelectronics, 8, 128-140 (2015). Review Paper

63. Q. Tang, C.P. Liang, K. Wu, A. Sandler, Y. Chen, “Real-time Epidural Anesthesia Guidance Using Optical Coherence Tomography Needle Probe,” Quantitative Imaging in Medicine and Surgery, 5, 118-124 (2015).

64. Z. Ding, C.P. Liang, Q. Tang, Y. Chen, “Quantitative single-mode fiber based PS-OCT with single input polarization state using Mueller matrix,” Biomedical Optics Express, 6, 1828-1843 (2015).

65. H. Jang, T.J. Pfefer, Y. Chen, “Solid hemoglobin-polymer phantoms for evaluation of biophotonic systems,” Optics Letters, 40, 4321-4324 (2015).

66. P. Ghassemi, J. Wang, A.J. Melchiorri, J.C. Ramella-Roman, S.A. Mathews, J.C. Coburn, B.S. Sorg, Y. Chen, T.J. Pfefer, “Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imaging,” Journal of Biomedical Optics, 20, 121312 (2015).

67. C.M. Piard, Y. Chen, J.P. Fisher, “Cell-Laden 3D Printed Scaffolds for Bone Tissue Engineering,” Clinical Reviews in Bone and Mineral Metabolism, 13, 245-255 (2015). Review Paper

68. Q. Tang, V. Tsytsarev, C.P. Liang, F. Akkentli, R.S. Erzurumlu, Y. Chen, “In Vivo Voltage-Sensitive Dye Imaging of Subcortical Brain Function,” Scientific Reports, 5, 17325 (2015).

69. M.S. Ozturk, C.W. Chen, R. Ji, L. Zhao, B.B. Nguyen, J.P. Fisher, Y. Chen, X. Intes, “Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues,” Annals of Biomedical Engineering, 44, 667-79 (2016). Review Paper

70. V. Tsytsarev, E. Pumbo, Q. Tang, C.W. Chen, Y. Chen, “Study of the cortical representation of whisker frequency selectivity using voltage-sensitive dye optical imaging,” IntraVital, 5, e1142637 (2016).

71. Q. Tang, V. Tsytsarev, A. Frank, Y. Wu, C.W. Chen, R.S. Erzurumlu, Y. Chen, “Depth-resolved Mesoscopic Voltage-Sensitive Dye Imaging of Brain Activation In Vivo.” Scientific Reports, 6, 25269 (2016).

72. P.M. Andrews, H.W. Wang, H. Guo, E. Anderson, R. Falola, Y. Chen, “Optical Coherence Tomography (OCT) of the Aging Kidney,” Experimental and Clinical Transplantation, doi: 10.6002/ect.2015.0212, Epub ahead of print (2016).

73. S.K. Han, C.W. Chen, K.M. Labus, C.M. Puttlitz, Y. Chen, A.H. Hsieh, “Optical Coherence Tomographic Elastography Reveals Mesoscale Shear Strain Inhomogeneities in the Annulus Fibrosus,” Spine, 41, E770-7 (2016).

74. Z. Ding, L. Jin, H.W. Wang, Q. Tang, H. Guo, Y. Chen, “Multi-modality Optical Imaging of Rat Kidney Dysfunction In vivo Responded to Various Ischemia Times,” Advances in Experimental Medicine and Biology, 923, 345-50 (2016).

75. P. Ghassemi, B. Wang, J. Wang, Q. Wang, Y. Chen, T.J. Pfefer, “Evaluation of Mobile Phone Performance for Near-Infrared Fluorescence Imaging,” IEEE Transactions in Biomedical Engineering, in press.

76. Z. Ding, Q. Tang, C.P. Liang, K. Wu, A. Sandler, H. Li, Y. Chen, “Imaging spinal structures with polarization-sensitive optical coherence tomography: Preliminary piglet model studies,” IEEE Photonics Journal, 8, 6804508 (2016).

77. Q. Tang, V. Tsytsarev, R.S. Erzurumlu, Y. Chen, “Mesoscopic Tomography for Depth-Resolved Imaging of Neural Activities,” Neurophotonics, 4, 011009 (2016). Review Paper

78. Q. Tang, J. Wang, A. Frank, J. Lin, Z. Li, C.W. Chen, L. Jin, H. Mashimo, B. Greenwald, Y. Chen, “Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography.” Biomedical Optics Express, 7, 5218-5232 (2016). Editor’s pick on Optical Coherence Tomography, December 2016

79. Vassiliy Tsytsarev, Fatih Akkentli, Elena Pumbo, Qinggong Tang, Yu Chen, Reha S. Erzurumlu, Dmitri B. Papkovsky, Planar implantable sensor for in vivo measurement of cellular oxygen metabolism in brain tissue, Journal of Neuroscience Methods, Volume 281, 1 April 2017, Pages 1-6, ISSN 0165-0270.

80. Z. Li, Q. Tang, L. Jin, P. M. Andrews and Y. Chen, “Monitoring Kidney Microanatomy Changes During Ischemia-Reperfusion Process Using Texture Analysis of OCT Images,” in IEEE Photonics Journal, vol. 9, no. 2, pp. 1-10, April 2017.

80. Qinggong Tang, Yi Liu, Vassiliy Tsytsarev, Jonathan Lin, Bohan Wang, Udayakumar Kanniyappan, Zhifang Li, and Yu Chen, “High-dynamic-range fluorescence laminar optical tomography (HDR-FLOT),” Biomed. Opt. Express 8, 2124-2137 (2017)

81. Okhil K. Nag, Michael H. Stewart, Jeffrey R. Deschamps, Kimihiro Susumu, Eunkeu Oh, Vassiliy Tsytsarev, Qinggong Tang, Alexander L. Efros, Roman Vaxenburg, Bryan J. Black, YungChia Chen, Thomas J. O’Shaughnessy, Stella H. North, Lauren D. Field, Philip E. Dawson, Joseph J. Pancrazio, Igor L. Medintz, Yu Chen, Reha S. Erzurumlu, Alan L. Huston, and James B. Delehanty, “Quantum Dot–Peptide–Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential,” ACS Nano, 2017, 11 (6), pp 5598–5613. Featured on Journal Cover

82. Qinggong Tang, Tadanobu Nagaya, Yi Liu, Jonathan Lin, Kazuhide Sato, Hisataka Kobayashi, Yu Chen, “Real-time monitoring of microdistribution of antibody-photon absorber conjugates during photoimmunotherapy in vivo,” Journal of Controlled Release 260, 154-163 (2017). Featured on Journal Cover.